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In healthy volunteers, plasma concentrations peak 6 to 24 hours (median, about 17 hours) after a single dose of Lariam. It has important information about Lariam and should be carried with you at all times while you take Lariam. falciparum malaria in pediatric patients is supported by evidence from adequate and well-controlled studies of Lariam in adults with additional data from published open-label and comparative trials using Lariam to treat malaria caused by P. If a significant loss of drug product is observed or suspected because of vomiting, a second full dose of Lariam should be administered to patients who vomit less than 30 minutes after receiving the drug. Ketoconazole should not be administered with Lariam or within 15 weeks of the last dose of Lariam due to the risk of a potentially fatal prolongation of the QTc interval (see WARNINGS). Experience with Lariam in pediatric patients weighing less than 20 kg is limited.
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